β-Sitosterol β-Sitosterol
Structural formula
| Business number | 01TY |
|---|---|
| Molecular formula | C29H50O |
| Molecular weight | 414.71 |
| label |
beta-sitosterol, Phytosterols, (3β)-Stigmaster-5-en-3-ol, 22,23-dihydrostistol, 24β-ethyl-5-cholesten-3βol, β-sitosterol, α-Dihydrofucosterol, 22,23-Dihydrostigmasterol, 24β-Ethyl-5-cholesten-3β-ol, 5-Stigmasten-3β-ol, Cinchol, Cytellin, (24R)-a-Stigmast-5-en-3β-ol, Textile softeners, gasoline emulsifiers and pigment dispersants, alcohol solvent |
Numbering system
CAS number:83-46-5
MDL number:MFCD00003631
EINECS number:201-480-6
RTECS number:WJ2600000
BRN number:1916165
PubChem number:24899468
Physical property data
1. Properties: White crystalline solid.
2. Density (g/mL, 20/4℃): 0.97
3. Relative vapor density (g/mL, air=1): Uncertain
4. Melting point (ºC): 140
5. Boiling point (ºC, normal pressure): 501.9
6. Boiling point (ºC, 5.2kPa): Uncertain
7. Refractive index: Uncertain
8. Flash point (ºC): 220.4
9. Specific rotation (º): [α]D25 -37° (C=2, in chloroform).
10. Autoignition point or ignition temperature (ºC): Uncertain
11. Vapor pressure (kPa, 25ºC): Uncertain
12. Saturation Vapor pressure (kPa, 60ºC): Uncertain
13. Heat of combustion (KJ/mol): Uncertain
14. Critical temperature (ºC): Uncertain
15. Critical pressure (KPa): Uncertain
16. Log value of oil-water (octanol/water) partition coefficient: Uncertain
17. Explosion upper limit (% , V/V): Uncertain
18. Lower explosion limit (%, V/V): Uncertain
19. Solubility: Insoluble in water, slightly soluble in Acetone and ethanol are soluble in benzene, chloroform, ethyl acetate, carbon disulfide, petroleum ether, acetic acid, etc.
Toxicological data
Ecological data
None yet
Molecular structure data
1. Molar refractive index: 129.21
2. Molar volume (cm3/mol): 424.3
3. Isotonic specific volume (90.2K ): 1051.0
4. Surface tension (dyne/cm): 37.6
5. Polarizability (10-24cm3): 51.22
Compute chemical data
1. Reference value for hydrophobic parameter calculation (XlogP): 9.3
2. Number of hydrogen bond donors: 1
3. Number of hydrogen bond acceptors: 1
4. Number of rotatable chemical bonds: 6
5. Number of tautomers: none
6. Topological molecule polar surface area 20.2
7. Number of heavy atoms: 30
8. Surface charge: 0
9. Complexity: 634
10. Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 9
12. Uncertain number of atomic stereocenters: 0
13. Determine the number of chemical bond stereocenters: 0
14. Number of uncertain chemical bond stereocenters: 0
15. Number of covalent bond units: 1
Properties and stability
Widely distributed in plants, it can be extracted from several vegetable oils or from rice bran oil.
Storage method
Used for sealed packaging in glass bottles or plastic bags and stored in a dry and dark place.
Synthesis method
1. Take Asparagus (Aparagvs Lucidus Lindl) / 3 volumes, cool and let stand overnight. Collect the precipitates, add 2.0% hot water to the filtrate to hydrolyze for several hours, and then filter out the insoluble materials after cooling. Combine this insoluble matter with the previously collected precipitate, add 5% and heat for hydrolysis. The hydrolyzate is extracted with diethyl ether, and the diethyl ether is recovered to dryness, which is the sitosterol enrichment.
2.It is made by extracting rice bran oil from legumes.
3. Tobacco: FC, 8, 32, 41, 43; BU, 1; can be isolated from wheat germ oil and corn oil.
4. Obtain platelets from ethanol.
Purpose
1. Sterols are a class of physiologically active substances. It can be used in medicine to promote wound healing, muscle hyperplasia and enhance capillary circulation. It can also be used to synthesize sterol hormones that regulate water, protein, sugar and inorganic salts. It is an important raw material for the production of steroid hormone drugs. It can also be used for skin nutrition and protection. In addition, it also has good prospects for the development and application of textile softeners, gasoline emulsifiers and pigment dispersants.
2.Sitosterol is non-toxic, non-irritating to the skin, has significant anti-inflammatory properties, and can be used to treat skin cancer and skin ulcers. Has antioxidant capacity. It has an auxiliary effect in inhibiting sweat gland secretion. Used in skin care products when combined with vitamins, it has conditioning effects, making the skin smooth and moist, and treating or delaying keratinization of the skin. It can also be used as an auxiliary in hair care products.
3.It has the functions of lowering cholesterol, relieving cough, eliminating phlegm, inhibiting tumors and repairing tissues. It is used for hypercholesterolemia, atherosclerosis and chronic tracheitis, as well as early cervical cancer and skin ulcers.
