4-Hydroxy-3-nitrobenzenearsonic acid 4-Hydroxy-3-nitrobenzenenearsonic Acid
Structural formula
| Business number | 03DB |
|---|---|
| Molecular formula | C6H6AsNO6 |
| Molecular weight | 263.04 |
| label |
3-nitro-4-hydroxyphenylarsonic acid, 3-nitro-4-hydroxy-phenylarsonic acid, roxarsenic, Lockshaw, 3-nitro-4-hydroxybenzenesarsenic acid, p-Hydroxym-nitrobenzarsonic acid, m-nitro-p-hydroxyphenylarsonic acid, 2-Nitrophenol-4-arsonic acid, 4-Hydroxy-3-nitrobenzenenearsonic acid, 3-Nitro-4-hydroxy-1-phenylarsonic acid, 3-Nitro-4-hydroxyphenylarsonic acid, Roxarson, Roxarsone, growth promoters, Feed additives |
Numbering system
CAS number:121-19-7
MDL number:MFCD00007112
EINECS number:204-453-7
RTECS number:CY5250000
BRN number:1976533
PubChem ID:None
Physical property data
1. Properties: white or light yellow needle-like or rhombohedral crystals
2. Melting point (℃): >300
3. Water solubility (g/100mL, 23°C): <0.1
4. Toxicity: Toxic
Toxicological data
None
Ecological data
None
Molecular structure data
None
Compute chemical data
1. Reference value for hydrophobic parameter calculation (XlogP): None
2. Number of hydrogen bond donors: 3
3. Number of hydrogen bond acceptors: 6
4. Number of rotatable chemical bonds: 1
5. Number of tautomers: 4
6. Topological molecule polar surface area 124
7. Number of heavy atoms: 14
8. Surface charge: 0
9. Complexity: 270
10. Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 0
12. Uncertain number of atomic stereocenters: 0
13. Determine the number of chemical bond stereocenters: 0
14. Number of uncertain chemical bond stereocenters: 0
15. Number of covalent bond units: 1
Properties and stability
1. Basic properties
White or light yellow needle-like or rhombohedral crystals. Easily soluble in methanol, ethanol, acetic acid, acetone and alkali, soluble in about 30 parts of boiling water, slightly soluble in cold water, very slightly soluble in dilute mineral acid, insoluble in ether and ethyl acetate. Melting point ≥300℃. Toxic, LD50 (�Rat, oral) 155mg/kg.
Storage method
2. Storage:
Seal and store in a dark place.
Synthesis method
1. Obtained from nitration of p-hydroxyphenylarsonic acid. Add p-hydroxyphenylarsonic acid and sulfuric acid into the reaction pot, stir and cool to below 0°C, slowly add the mixed acid, continue stirring for 1 hour, put it into ice water to precipitate, filter and dry to obtain 4-hydroxy-3-nitrobenzene Arsinic acid.
2.It is prepared from p-hydroxyaniline as raw material through diazotization, arsenization and nitration; it can also be made from phenol as raw material through arsenization and nitration be made of.
Purpose
1. Used as an intermediate in organic synthesis and a reagent for the determination of cadmium. The oral LD50 in rats is 155 mg/kg
2.Broad-spectrum antibacterial and antiprotozoal drugs. It can improve feed efficiency, promote growth, prevent and treat various bacterial and protozoal diseases, and promote pigmentation and ketone body quality.
