Aminoglutethimide DL-Aminogluthamide
Structural formula
| Business number | 03JU |
|---|---|
| Molecular formula | C13H16N2O2 |
| Molecular weight | 232.28 |
| label |
triamperidone, Trifenadone, fenacetate, aminoglumide, 3-ethyl-3-(4-aminophenyl)-2,6-piperidinedione, Phenylethyl piperidone, DL-Aminoglutethimide, inhibitors, inhibitor |
Numbering system
CAS number:125-84-4
MDL number:None
EINECS number:None
RTECS number:None
BRN number:None
PubChem ID:None
Physical property data
1. Character: white crystal, bitter taste
2. Solubility: Hardly soluble in water, easily soluble in organic solvents
Toxicological data
None
Ecological data
None
Molecular structure data
5. Molecular property data:
1. Molar refractive index: 64.58
2. MooreVolume (m3/mol): 197.9
3. isotonic specific volume (90.2K):517.4
4. Surface Tension (dyne/cm):46.6
5. Polarizability（10-24cm3):32.41
Compute chemical data
1. Reference value for hydrophobic parameter calculation (XlogP):6
2. Number of hydrogen bond donors: 4
3. Number of hydrogen bond acceptors: 6
4. Number of rotatable chemical bonds: 17
5. Number of tautomers: 4
6. Topological molecular polar surface area (TPSA):132
7. Number of heavy atoms: 34
8. Surface charge: 0
9. Complexity: 684
3. Number of hydrogen bond acceptors: 6
4. Number of rotatable chemical bonds: 17
5. Number of tautomers: 4
6. Topological molecular polar surface area (TPSA):132
7. Number of heavy atoms: 34
8. Surface charge: 0
9. Complexity: 684
10. Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 0
12. The number of uncertain atomic stereocenters: 4
13. Determine the number of stereocenters of chemical bonds: 0
14. Uncertain number of chemical bond stereocenters: 0
15. Number of covalent bond units: 1
Properties and stability
Basic properties: It inhibits the cleavage enzyme system that converts cholesterol into pregnenolone.
Storage method
Storage: Store at room temperature.
Synthesis method
Brief description of production method: It is prepared from 2-p-chlorophenylbutanamide as raw material.
Purpose
Purpose: It is an adrenocortical hormone inhibitor and anti-cancer drug. Also used in hypercortisolism and advanced breast cancer after menopause or oophorectomy
y: 宋体”>10. Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 0
12. The number of uncertain atomic stereocenters: 4
13. Determine the number of stereocenters of chemical bonds: 0
14. Uncertain number of chemical bond stereocenters: 0
15. Number of covalent bond units: 1
Properties and stability
Basic properties: It inhibits the cleavage enzyme system that converts cholesterol into pregnenolone.
Storage method
Storage: Store at room temperature.
Synthesis method
Brief description of production method: It is prepared from 2-p-chlorophenylbutanamide as raw material.
Purpose
Purpose: It is an adrenocortical hormone inhibitor and anti-cancer drug. Also used in hypercortisolism and advanced breast cancer after menopause or oophorectomy
