Vinblastine sulfate
Structural formula
| Business number | 03W8 |
|---|---|
| Molecular formula | C46H60N4O13S |
| Molecular weight | 909.05 |
| label |
Vincaleukoblastine sulfate salt |
Numbering system
CAS number:143-67-9
MDL number:MFCD00082457
EINECS number:205-606-0
RTECS number:YY8400000
BRN number:3659812
PubChem number:24278771
Physical property data
1. Physical property data:
1. Melting point (ºC): 267ºC
2. Specific optical rotation (º): -21.7 º
Toxicological data
2. �Physics data:
1, acute toxicity: rat oral LD50: 305 mg/kg;
Rat abdominal cavity LD50: 1 mg/kg;
Rat subcutaneous LD50: 355 mg/kg;
Rat veinLD50：37 mg/kg;
Mice orallyLD50: 423 mg/kg;
Mouse abdominal cavity LD50: 2700 ug/kg；
Mouse subcutaneous LD50: 324 mg/kg.
Ecological data
3. Ecological data:
Other harmful Effect: This substance may be harmful to the environment, and special attention should be paid to water bodies.
Molecular structure data
None
Compute chemical data
4. Calculated chemical data:
1. Hydrogen Bonding Number of donors: 5
2. Hydrogen Bonding Number of receptors: 16
3. Rotatable Number of chemical bonds: 10
4. Topological molecules Polar surface area (TPSA）：229
5. Heavy atoms Quantity: 64
6. Surface charge ：0
7. Complexity ：1780
8. Isotope atomic number:0
9. Determine the number of atomic stereocenters:9
10. Uncertain number of atomic stereocenters:0
11. Determine the number of stereocenters of chemical bonds:0
12. Uncertain number of chemical bond stereocenters:0
13. Number of covalent bond units: 2
Properties and stability
Stable under normal temperature and pressure.
Storage method
Save at 2-8ºC.
Synthesis method
None
Purpose
1.Anti-tumor drugs, used to treat Hodgkin’s disease and chorioepithelial carcinoma, and also have certain effects on lymphosarcoma, acute leukemia, breast cancer, etc.. 2.Anti-tumor drug for malignant lymphoma
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1.Anti-tumor drugs, used to treat Hodgkin’s disease and chorioepithelial carcinoma, and also have certain effects on lymphosarcoma, acute leukemia, breast cancer, etc..
2.Anti-tumor drug for malignant lymphoma
