Methandrosterone
Structural formula
| Business number | 01H7 |
|---|---|
| Molecular formula | C20H28O2 |
| Molecular weight | 300.44 |
| label |
Methandrostenone, Dehydrotestosterone, Dehydromethyltestosterone, 17BETA-Hydroxy-17-methylestro-1,4-dien-3-one, Testosterone, 1-Dehydro-17α-methyltestosterone, Dianabol, Methandienone, Methandrostenolone |
Numbering system
CAS number:72-63-9
MDL number:MFCD00003650
EINECS number:200-787-2
RTECS number:BV8000000
BRN number:2056255
PubChem number:24879519
Physical property data
1. Character:White or slightly yellow crystal powder, odorless
2. Density (g/mL,25/4℃): Unsure
3. Relative vapor density (g/mL,AIR=1): Unsure
4. Melting point (ºC):165 -166
5. Boiling point (ºC,Normal pressure): Uncertain
6. Boiling point (ºC, 5.2 kPa): Unsure
7. Refractive index:Not sure
8. Flash Point (ºC): Unsure
9. Specific optical rotation (º): Unsure
10. Autoignition point or ignition temperature (ºC): Unsure
11. Vapor pressure (kPa,25 ºC): Unsure
12. Saturated vapor pressure (kPa,60 ºC): Unsure
13. Heat of combustion (KJ/mol): Unsure
14. Critical temperature (ºC): Unsure
15. Critical pressure (KPa): Unsure
16. Oil and water (octanol/Log value of the partition coefficient of water: Uncertain
17. Explosion limit (%,V/V): Unsure
18. Lower explosion limit (%,V/V): Unsure
19. Solubility:Almost insoluble in water, soluble in ethanol, chloroform, slightly soluble in ether
Toxicological data
Acute toxicity: Rat oral LD50: >1 mg/kg; Rat intraperitoneal LD50：425 mg/kg;
Oncogenic: MaleOral SutraTDLo：561 mg/kg/7Y-C;
Reproduction: Male Oral PeriodTDLo：13 mg/kgSEX/DURATION : male 60 day(s) pre-mating;
Rat oral narcosisTDLo：200 mg/kgSEX/DURATION: female 10 day(s) pre-mating;
Rat oral passageTDLo： 200 mg/kgSEX/DURATION: male 10 day(s) pre-mating；
Subcutaneous injection in ratsTDLo：7 mg/kgSEX/DURATION: female 14 day(s) pre-mating;
Mutagenic: Mouse oral Display Sexual Death Test： 200 mg/kg/10D (Intermittent);
Ecological data
None
Molecular structure data
1. Molar refractive index:87.68
2. Molar volume (m3/mol）：266.3
3. isotonic specific volume (90.2K):689.6
4. Surface Tension (dyne/cm):44.9
5. Polarizability(10-24cm3）：34.76
Compute chemical data
1. Hydrophobic parameters Calculate reference value (XlogP）：3.6
2. Hydrogen Bonding Number of donors: 1
3. Hydrogen Bonding Number of receptors: 2
4. Rotatable Number of chemical bonds: 0
5. Interchange Number of isomers: 3
6. Topological molecular polar surface area ( TPSA):37.3
7. Heavy atoms Quantity: 22
8. Surface charge ：0
9. Complexity ：589
10. Isotope atomic number:0
11. Determine the number of atomic stereocenters:6
12. Number of uncertain atomic stereocenters:0
13. Determine the number of stereocenters of chemical bonds:0
14. Uncertain number of chemical bond stereocenters:0
15. Number of covalent bond units: 1
Properties and stability
None
Storage method
None
Synthesis method
Prepared from sisal saponin as raw material
Purpose
Used for osteoporosis, recovery period of chronic wasting disease, severe infection, burns, etc. Negative nitrogen balance, promotes the growth of premature infants and immature infants, etc. In addition, it can also be used for fractures that are not easy to heal, hypercholesterolemia, postpartum weakness, etc. The preparation is a tablet.
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