Actinomycin D Actinomycin D
Structural formula
| Business number | 0144 |
|---|---|
| Molecular formula | C62H86N12O16 |
| Molecular weight | 1255.42 |
| label |
dactinomycin, Dactinomycin D, Actinomycin C1, Vulcanizing agent double-25, vincristine, cyclophosphamide, Actinomycin D, Actinomycin IV, Actinomycin D(8CI,9CI), Dactinomycin(USAN), AD(VAN) |
Numbering system
CAS number:50-76-0
MDL number:MFCD00005033
EINECS number:200-063-6
RTECS number:AU1575000
BRN number:605235
PubChem number:24890541
Physical property data
1. Character:Bright red crystalline powder,Odorless,Hygroscopic. Exposure to light, heat or oxidants can reduce its potency.
2. Density (g/mL,25/4℃ ): Undetermined
3. Relative vapor density (g /mL,AIR= 1): Undetermined
4. Melting point (ºC):251-253 °C
5. Boiling point (ºC,Normal pressure): Undetermined
6. Boiling point (ºC, 5.2 kPa): Undetermined
7. Refractive index:Undetermined
8. Flash point (ºC): Undetermined
9. Specific optical rotation (º ):[α]18D-315°(0.02%, methanol)
10. Autoignition point or ignition temperature (ºC): Undetermined8. Surface charge: 0
9. Complexity: 3030
10. Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 0
12. The number of uncertain atomic stereocenters: 10
13. Determine the number of stereocenters of chemical bonds: 0
14. Uncertain number of chemical bond stereocenters: 0
15. Number of covalent bond units: 1
Properties and stability
None
Storage method
Sealing4 Store in a dry place away from light.
Synthesis method
This product is a polypeptide antibiotic produced by actinomycetes. Isolated from Guilin soil in my countryStr. melanochromogehesSTRAIN The product extracted from the fermentation broth is called dactinomycin, which is similar to actinomycin reported abroadDSame.
Purpose
Metabolism inhibitors, cytoplasmic membrane research. This product has a significant effect on malignant hydatidiform mole, Wilms tumor, Hodgkin’s disease, testicular tumors, rhabdomyosarcoma, neuroblastoma and reticulum cell sarcoma. efficient. It also has certain curative effects on cervical cancer, ovarian cancer, breast cancer and digestive tract cancer. Combined use with radiotherapy can increase the sensitivity of radiotherapy.
Synthesis method
This product is a polypeptide antibiotic produced by actinomycetes. Isolated from Guilin soil in my countryStr. melanochromogehesSTRAIN The product extracted from the fermentation broth is called dactinomycin, which is similar to actinomycin reported abroadDSame.
Purpose
Metabolism inhibitors, cytoplasmic membrane research. This product has a significant effect on malignant hydatidiform mole, Wilms tumor, Hodgkin’s disease, testicular tumors, rhabdomyosarcoma, neuroblastoma and reticulum cell sarcoma. efficient. It also has certain curative effects on cervical cancer, ovarian cancer, breast cancer and digestive tract cancer. Combined use with radiotherapy can increase the sensitivity of radiotherapy.
