1,2-Dipalmitoyl-sn-glycero-3-phosphocholine
Structural formula
| Business number | 01CY |
|---|---|
| Molecular formula | C40H80NO8P |
| Molecular weight | 734.05 |
| label |
Cofocilil palmitate, 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine, L-α-Phosphatidylcholine, dipalmitoyl, Other medicines |
Numbering system
CAS number:63-89-8
MDL number:MFCD00036903
EINECS number:200-567-6
RTECS number:None
BRN number:None
PubChem number:24898128
Physical property data
1. Properties: Crystallized from hot diisobutyl ketone
2. Density (g/mL, 25/4℃): Uncertain
3. Relative vapor density (g/mL, air=1): Uncertain
4. Melting point (ºC): 229-229.5
5. Boiling point (ºC, normal pressure): Uncertain
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6. Boiling point (ºC, 5.2kPa): Uncertain
7. Refractive index: Uncertain
8. Flash point (ºC): Uncertain
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9. Specific rotation (º): Uncertain
10. Autoignition point or ignition temperature (ºC): Uncertain
11. Vapor pressure (kPa , 25ºC): Uncertain
12. Saturated vapor pressure (kPa, 60ºC): Uncertain
13. Heat of combustion (KJ/mol): Uncertain
14. Critical temperature (ºC): Uncertain
15. Critical pressure (KPa): Uncertain
16. Log value of oil-water (octanol/water) partition coefficient : Uncertain
17. Explosion upper limit (%, V/V): Uncertain
18. Explosion lower limit (%, V/V): Uncertain
19. Solubility: Easily soluble in chloroform, hot diisobutyl ketone or hot dioxane. Easily emulsified in water. Solubility at 22-23°C (g/100ml): ethanol 1.5, ether 0.02, acetone 0.02, pyridine 1.1, acetic acid 4.0, methanol 1.4
Toxicological data
None yet
Ecological data
None yet
Molecular structure data
None yet
Compute chemical data
1. Hydrophobic parameter calculation reference value (XlogP): 13.5
2. Number of hydrogen bond donors: 0
3. Number of hydrogen bond acceptors: 8
4. Number of rotatable chemical bonds: 40
5. Topological molecular polar surface area (TPSA): 111
6. Number of heavy atoms: 50
7. Surface charge: 0
8. Complexity: 826
9. Number of isotope atoms.�0
10. Determine the number of atomic stereocenters: 1
11. Uncertain number of atomic stereocenters: 0
12. Determine the chemical bond configuration Number of centers: 0
13. Number of uncertain chemical bond stereocenters: 0
14. Number of covalent bond units: 1
Properties and stability
None yet
Storage method
This product should be sealed and stored dry at -18℃.
Synthesis method
Synthetic surfactant, composed of palm bile, cetyl alcohol and Tyloxapol )composition.
Purpose
Pulmonary surfactant, organic reagents, pharmaceutical intermediates;
