Piperazine Citrate
Structural formula
| Business number | 03WE |
|---|---|
| Molecular formula | C24H46N6O14 |
| Molecular weight | 642.65 |
| label |
piperazine citrate, tri-Piperazine dicitrate |
Numbering system
CAS number:144-29-6
MDL number:MFCD00038961
EINECS number:205-622-8
RTECS number:TL3485000
BRN number:None
PubChem number:24870338
Physical property data
1. Physical property data
1. Characteristics: White crystalline powder or translucent crystalline particles.
2. Solubility:Easily soluble in water, very slightly soluble in methanol, insoluble in ethanol, ether, chloroform and benzene.
3. Boiling point (ºC,normal pressure): 182-187 ºC (decomposition)
Toxicological data
2. Toxicological data:
1, acute toxicity: oral administration to rats LD50 : 11200 mg/kg;
Small Rat oral LD50: 8500 mg/kg;
Small Mouse abdominal cavity LD50: 3548 mg/kg;
Small Mouse intravenous LDLo: 100 mg/kg;
Rabbit Intravenous LDLo: 175 mg/kg.
Ecological data
3. Ecological data:
Other harmful Effect: This substance may be harmful to the environment, and special attention should be paid to water bodies.
Molecular structure data
None
Compute chemical data
4. Calculated chemical data:
1. Hydrogen Bonding Number of donors: 6
2. Hydrogen Bonding Number of receptors: 9
3. Rotatable Number of chemical bonds: 5
4. Topological molecules Polar surface area (TPSA）：156
5. Heavy atoms Quantity: 19
6. Surface charge ：0
7. Complexity ：254
8. Number of isotope atoms: 0
9. Determine the number of atomic stereocenters:0
10. Uncertain number of atomic stereocenters:0
11. Determine the number of stereocenters of chemical bonds:0
12. Uncertain number of chemical bond stereocenters:0
13. Number of covalent bond units: 2
Properties and stability
Stable under normal temperature and pressure. SPAN>
Storage method
Save in a dry and cool place.
Synthesis method
Dissolve piperazine hexahydrate in distilled water, add activated carbon in 50-60℃Decolorize for half an hour and filter. Add citrate to the filtrate and add citric acid to 88-90 -family: 宋体”>℃Stir 1.5 hours. Cool to 35℃, add ethanol, cool and crystallize, filter, and dry to obtain the finished product.
Purpose
1.Anthelmintics, used for pinworm and roundworm infections.
2. Used as an anthelmintic
AMILY: 宋体; mso-bidi-font-family: 宋体”>℃Stir 1.5 hours. Cool to 35℃, add ethanol, cool and crystallize , filtered and dried to obtain the finished product.
Purpose
1.Anthelmintics, used for pinworm and roundworm infections.
2. Used as an anthelmintic
