Spermidine Spermidine
Structural formula
| Business number | 03HZ |
|---|---|
| Molecular formula | C7H19N3 |
| Molecular weight | 145.25 |
| label |
N-(3-aminopropyl)-1,4-butanediamine, N-(3-Aminopropyl)-1,4-butanediamine, N-(γ-Aminopropyl)tetramethylenediamine, Genetic engineering research reagents |
Numbering system
CAS number:124-20-9
MDL number:MFCD00008229
EINECS number:204-689-0
RTECS number:EJ7000000
BRN number:1698591
PubChem number:24899434
Physical property data
1. Boiling point: 128-130 (1866pa)
2. Melting point: 22-25
3. Solubility: soluble in water, alcohol and ether
4. Density (d254) : 0.925
5. Refractive index (n20 D): 1.4785-1.4805
6. Properties: liquid, hygroscopic 7. Flash point (ºC): >112
Toxicological data
1. Acute toxicity: Oral LD3O in mice: >1gm/kg
Subcutaneous LD3O in mice: 450mg/kg
Intravenous LD5O in mice: 78mg/kg
2. Other multi-dose toxicity: chicken oral TDLO: 9504gm/kg/14D-C
3. Mutagenicity: Bacillus subtilis mutation test system: 50mg/L
Rat liver mutation test system: 4mmoL/L
Mouse ascites tumor DNA inhibition test system: 2mmoL/L
Mouse liver DNA inhibition test system: 2mmoL/ L
Hamster ovary DNA damage test system: 300umoL/L is corrosive
Ecological data
None
Molecular structure data
5. Molecular property data:
1. Molar refractive index: 45.14
2. Molar volume (cm3/mol): 160.2
3. Isotonic specific volume (90.2K): 396.6
4. Surface tension (dyne/cm): 37.5
5. Polarizability (10-24cm3): 17.89
Compute chemical data
1. Reference value for hydrophobic parameter calculation (XlogP): -1
2. Number of hydrogen bond donors: 3
3. Number of hydrogen bond acceptors: 3
p>
4. Number of rotatable chemical bonds: 7
5. Number of tautomers: none
6. Topological molecule polar surface area 64.1
7. Number of heavy atoms: 10
8. Surface charge: 0
9. Complexity: 56.8
10. Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 0
12. Uncertain number of atomic stereocenters: 0
13. Determine the number of chemical bond stereocenters: 0
14. Number of uncertain chemical bond stereocenters: 0
15. Number of covalent bond units: 1
Properties and stability
1. Found in oriental tobacco leaves.
Storage method
Storage: sealed and stored at 2~8℃
Synthesis method
1. Tobacco: OR, 27.
Purpose
.Purpose: Inhibit neuronal NO synthase (nNOS). Binds and precipitates DNA; also used to purify DNA-binding proteins. Stimulates T4 polynucleotide kinase activity. biochemical research
