Sulfamethoxypyridazine Sulfamethoxypyridazine
Structural formula
| Business number | 01QX |
|---|---|
| Molecular formula | C11H12N4O3S |
| Molecular weight | 280.3 |
| label |
N1-(6-Methoxypyridazin-3-yl)sulfanilamide |
Numbering system
CAS number:80-35-3
MDL number:MFCD00057372
EINECS number:201-272-5
RTECS number:WP0400000
BRN number:277076
PubChem ID:None
Physical property data
1. Character: light yellow crystal, easy to change color when exposed to light
2. Density (g/mL, 25/4℃): Uncertain
3. Relative vapor density (g/mL, air=1): Uncertain
4. Melting point (ºC): 180～183℃
5. Boiling point (ºC, normal pressure): Uncertain
6. Boiling point (ºC, 5.2kPa): Uncertain
7. Refractive index: Uncertain
8. Flash point (ºC): Uncertain
9. Specific rotation (º): Uncertain
10. Autoignition point or ignition temperature (ºC): Uncertain
11. Vapor pressure ( kPa, 25ºC): Uncertain
12. Saturated vapor pressure (kPa, 60ºC): Uncertain
13. Heat of combustion (KJ/mol): Uncertain
14. Critical temperature (ºC): Uncertain
15. Critical pressure (KPa): Uncertain
16. Oil-water (octanol/water) partition coefficient relationship Value: Uncertain
17. Explosion upper limit (%, V/V): Uncertain
18. Explosion lower limit (%, V/V): Uncertain
19. Solubility: Insoluble in cold water, slightly soluble in boiling water
Toxicological data
None yet
Ecological data
None yet
Molecular structure data
1. Molar refractive index: 69.51
2. Molar volume (cm3/mol): 191.2
3. Isotonic specific volume (90.2K ): 563.0
4. Surface tension (dyne/cm): 75.0
5. Polarizability (10-24cm3): 27.55
Compute chemical data
1. Reference value for hydrophobic parameter calculation (XlogP): None
2. Number of hydrogen bond donors: 2
3. Number of hydrogen bond acceptors: 7
4. Number of rotatable chemical bonds: 4
5. Number of tautomers: 2
6. Topological molecule polar surface area 116
7. Number of heavy atoms: 19
8. Surface charge: 0
9. Complexity: 376
10. Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 0
12. Uncertain number of atomic stereocenters: 0
13. Determine the number of chemical bond stereocenters: 0
14. Number of uncertain chemical bond stereocenters: 0
15. Number of covalent bond units: 1
Properties and stability
None yet
Storage method
This product should be kept sealed.
Synthesis method
After cyclization of maleic anhydride and hydrazine sulfate, chlorination, condensation with sulfonamide, and then methyl Prepared by oxidation.
Purpose
One of the sulfa drugs, its antibacterial efficacy is equal to that of sulfadiazine. It was eliminated due to its serious side effects.
