γ-linolenic acid
Structural formula
| Business number | 0596 |
|---|---|
| Molecular formula | C18H30O2 |
| Molecular weight | 278.43 |
| label |
gamma-linolenic acid, All cis-6,9,12-octadecatrienoic acid, cis,cis,cis-6,9,12-Octadecatrienoic acid, Ganmolenic acid, acidic solvent |
Numbering system
CAS number:506-26-3
MDL number:MFCD00065718
EINECS number:None
RTECS number:None
BRN number:1712253
PubChem number:24896312
Physical property data
1. Properties: colorless or light yellow oil
2. Density (g/ cm3, 25/4℃): 0.92
3. Relative vapor density (g/cm3, air=1): Undetermined
4. Melting point (ºC): Undetermined
5 . Boiling point (ºC, normal pressure): 379.5
6. Boiling point (ºC, 5.2kPa): Undetermined
7. Refractive index (n20D): 1.471
8. Flash point (ºC): 110
9. Specific rotation (º): Undetermined
10. Autoignition point or ignition temperature (ºC): Undetermined
11. Vapor pressure (kPa, 25ºC): Undetermined
12 . Saturated vapor pressure (kPa, 60ºC): Undetermined
13. Heat of combustion (KJ/mol): Undetermined
14. Critical temperature (ºC): Undetermined
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15. Critical pressure (KPa): Undetermined
16. Log value of oil-water (octanol/water) partition coefficient: Undetermined
17. Explosion upper limit (%, V/V): Undetermined
18. Lower explosion limit (%, V/V): Undetermined
19. Solubility: Insoluble in water and ethanol, soluble in in a variety of organic solvents.
Toxicological data
Ecological data
This substance may be harmful to the environment, and special attention should be paid to water bodies.
Molecular structure data
1. Molar refractive index: 87.17
2. Molar volume (cm3/mol): 301.1
3. Isotonic specific volume (90.2K ): 731.7
4. Surface tension (dyne/cm): 34.8
5. Polarizability (10-24cm3): 34.56
Compute chemical data
1. Hydrophobic parameter calculation reference value (XlogP): 5.9
2. Number of hydrogen bond donors: 1
3. Number of hydrogen bond acceptors: 2
4. Number of rotatable chemical bonds: 13
5. Number of tautomers:
6. Topological molecular polar surface area (TPSA): 37.3
7. Number of heavy atoms: 20
8. Surface charge: 0
9. Complexity: 301
10. Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 0
12. Uncertain number of atomic stereocenters: 0
13. Determine the stereocenter of chemical bonds Number: 3
14. Number of uncertain chemical bond stereocenters: 0
15. Number of covalent bond units: 1
Properties and stability
1. Use and store according to specifications. It will not decompose and avoid contact with oxides.
2. Found in tobacco leaves.
Storage method
To prevent oxidation, the finished product must be protected from light and air, and sealed and packed with nitrogen. For low temperature storage, it is best to use soft capsules. Storage temperature -18ºC
Synthesis method
γ-Linolenic acid is one of the higher unsaturated fatty acids necessary for the human body. It is converted from linoleic acid in the human body. Found in the seed oil of evening primrose. Nowadays, it is gradually turning to be obtained by microbial fermentation, such as from Mortierlla isabellina, M. vinacea, M. rammanniana and other strains in the genus Mortierella, especially the Mertierella strain, with a higher yield. Regardless of the extraction method or fermentation method, freeze crystallization, urea inclusion method, silver nitrate column chromatography and other processes can be used for separation and purification. GLA is the precursor substance of prostaglandins and other substances in the human body, and is also one of the building blocks of cell biofilms.
Purpose
Can be used as a nutritional supplement. It is an excellent conditioner and nutritional supplement in skin care products. It can improve the hydration and elasticity of the skin, promote blood circulation and cell metabolism. Used in hair growth tinctures to eliminate dandruff, stimulate hair growth and give hair shine.