2-Chloropyridine 2-Chloropyridine
Structural formula
| Business number | 02YP |
|---|---|
| Molecular formula | C5H4ClN |
| Molecular weight | 113.54 |
| label |
2-Chloropyridine 99﹪, 2-Chloro-pyridin, o-Chloropyridine, α-Chloropyridine, 2clpy, Alpha-Chloropyridine, Pyridine, 2-chloro-, 2-Chloropyridine,99% |
Numbering system
CAS number:109-09-1
MDL number:MFCD00006228
EINECS number:203-646-3
RTECS number:US5950000
BRN number:105788
PubChem number:24855927
Physical property data
1. Characteristics: Colorless liquid.
2. Density (g/mL,25℃） ：1.2
3 . Relative vapor density (g/mL,air =1) : Undetermined
4. Melting point (ºC): -46
5. Boiling point (ºC,normal pressure): 168
6. Boiling point (ºC, 95.18kPa)：166
7. Refractive index (D20)：1.532
8. Flashpoint (ºC):65
9. Specific optical rotation (ºC): Undetermined
10. Autoignition point or ignition temperature (ºC):Undetermined
11. Vapor pressure (mmHg, 20ºC): 1.7
12. Saturated vapor pressure (kPa, 55 ℃)1.60
13. Heat of combustion (KJ/mol): Undetermined
14. Critical temperature (ºC): Undetermined
2, Mutagenicity
Microbial Salmonella Typhimurium mutation: 5mg/plate;
Sex chromosome loss and non-disjunction test in yeast cells: 4000ppm
Mouse lymphocyte mutation: 1920mg/L;
Mouse lymphocyte gene mutation: 400mg/L;
Cytogenetic analysis of mouse lymphocytes: 1980mg/L;
Ecological data
This substance is slightly harmful to water.
Molecular structure data
None
Compute chemical data
1. Reference value for hydrophobic parameter calculation (XlogP): None
2. Number of hydrogen bond donors: 0
3. Number of hydrogen bond acceptors: 1
4. Number of rotatable chemical bonds: 0
5. Number of tautomers: none
6. Topological molecule polar surface area 12.9
7. Number of heavy atoms: 7
8. Surface charge: 0
9. Complexity: 56
10. Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 0
12. Uncertain number of atomic stereocenters: 0
13. Determine the number of chemical bond stereocenters: 0
14. Number of uncertain chemical bond stereocenters: 0
15. Number of covalent bond units: 1
Properties and stability
Avoid contact with strong oxidants and acids.
Storage method
Stored in a cool, ventilated warehouse. Keep away from fire and heat sources. They should be stored separately from oxidants, acids, and food chemicals, and avoid mixed storage. Equipped with the appropriate variety and quantity of fire equipment. The storage area should be equipped with emergency release equipment and suitable containment materials.
Synthesis method
It is prepared by Sandmann reaction using 2-aminopyridine.
Purpose
Intermediates of antifungal agents such as pyrithione.
Protective equipment. The storage area should be equipped with emergency release equipment and suitable containment materials.
Synthesis method
It is prepared by Sandmann reaction using 2-aminopyridine.
Purpose
Intermediates of antifungal agents such as pyrithione.