3-aminosalicylic acid
Structural formula
| Business number | 05TZ |
|---|---|
| Molecular formula | C7H7NO3 |
| Molecular weight | 153.14 |
| label |
3-Amino-ortho-hydroxybenzoic acid, 3-Aminosalic acid, 3-Amino-2-hydroxybenzoic acid, Medicine |
Numbering system
CAS number:570-23-0
MDL number:MFCD00010299
EINECS number:209-328-0
RTECS number:None
BRN number:2090427
PubChem number:24855412
Physical property data
1. Physical property data
1. Appearance: white powder, slight acetone smell
2. Melting point (℃):240
3. Solubility:Almost insoluble in water and benzene, slightly soluble in ether and propyl ether
ketone, slightly soluble in Ethanol, dissolved in sodium bicarbonate or phosphoric acid solution
Toxicological data
None
Ecological data
3. Ecological data:
1, other harmful effects: This substance may be harmful to the environment, special attention should be paid to water bodies.
Molecular structure data
5. Molecular property data: 1. Molar refractive index: 39.30 2. Molar volume ( m3/mol）：102.6 3. isotonic specific volume (90.2K):310.2 4. Surface Tension (dyne/cm):83.3 5. Polarizability（10-24cm3):15.57
Compute chemical data
1. Reference value for hydrophobic parameter calculation (XlogP): None
2. Number of hydrogen bond donors: 3
3. Number of hydrogen bond acceptors: 4
4. Number of rotatable chemical bonds: 1
5. Number of tautomers: 9
6. Topological molecule polar surface area 83.6
7. Number of heavy atoms: 11
8. Surface charge: 0
9. Complexity: 160
10. Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 0
12. Uncertain number of atomic stereocenters: 0
13. Determine the number of chemical bond stereocenters: 0
14. Number of uncertain chemical bond stereocenters: 0
15. Number of covalent bond units: 1
Properties and stability
Stability and reactivity:
Materials to avoid: Oxides.
Products to be decomposed: carbon monoxide and carbon dioxide, nitrogen oxides.
Storage method
Storage:
Seal the secret container and store it in a sealed main container in a cool place Dry position.
Synthesis method
None
Purpose
1. Purpose
Applicable to acute exudative pulmonary tuberculosis and mucosal tuberculosis Waiting for illness. Usually with
Streptomycin and isoniazid are used together to Enhance efficacy.