D-(+)-Biotin D-(+)-Biotin
Structural formula
| Business number | 019V |
|---|---|
| Molecular formula | C10H16N2O3S |
| Molecular weight | 244.32 |
| label |
BiosII, Coenzyme R, D-Biotin, Vitamin B7, Vitamin H, Reagents for immunological research |
Numbering system
CAS number:58-85-5
MDL number:MFCD00005541
EINECS number:200-399-3
RTECS number:XJ9088200
BRN number:86838
PubChem number:24891778
Physical property data
1. Properties: colorless, slender needle-shaped crystals. The pure product is stable at room temperature and in the air. It can be stable for several months in neutral or moderately acidic solutions, unstable in alkaline solutions, aqueous solutions are prone to mold growth, and acidic solutions can be heated and sterilized.
2. Density (g/mL, 25/4℃): Undetermined
3. Relative vapor density (g/mL, air=1): Undetermined
4. Melting point (ºC): 232～233
5. Boiling point (ºC, normal pressure): Undetermined
6. Boiling point (ºC, 5.2kPa): Undetermined
7. Refractive index: Undetermined
8. Flash point (ºC): Undetermined
9. Specific rotation (º): + 91° (C=1, in 0.1mol/L sodium hydroxide solution)
10. Autoignition point or ignition temperature (ºC): Undetermined
11. Vapor pressure ( kPa, 25ºC): Undetermined
12. Saturated vapor pressure (kPa, 60ºC): Undetermined
13. Heat of combustion (KJ/mol): Undetermined
14. Critical temperature (ºC): Undetermined
15. Critical pressure (KPa): Undetermined
16. Oil-water (octanol/water) partition coefficient pair Value: Undetermined
17. Explosion upper limit (%, V/V): Undetermined
18. Explosion lower limit (%, V/V): Undetermined
19. Solubility: Easily soluble in hot water and dilute alkali solution, insoluble in other general organic solvents.
Toxicological data
1. Reproductive toxicity: Female rats subcutaneous TDLo: 200mg/kg, 14-15 days after conception; male rats subcutaneous TDLo: 100mg/kg, 1 day before mating; Female rats subcutaneous TDLo: 200mg/kg, 1-2 days later Pregnancy; Oral TDLo for female mice: 17mg/kg, conception occurs after 1-17 days
Ecological data
None yet
Molecular structure data
1. Molar refractive index: 60.88
2. Molar volume (cm3/mol): 192.7
3. Isotonic specific volume (90.2K ): 501.6
4. Surface tension (dyne/cm): 45.9
5. Polarizability (10-24cm3): 24.13
Compute chemical data
1. Reference value for hydrophobic parameter calculation (XlogP): 0.3
2. Number of hydrogen bond donors: 3
3. Number of hydrogen bond acceptors:3
4. Number of rotatable chemical bonds: 5
5. Number of tautomers: 3
6. Topological molecular polar surface area (TPSA) : 78.4
7. Number of heavy atoms: 16
8. Surface charge: 0
9. Complexity: 298
10 , Number of isotope atoms: 0
11. Number of determined atomic stereocenters: 3
12. Number of uncertain atomic stereocenters: 0
13. The number of determined stereocenters of chemical bonds: 0
14. The number of uncertain stereocenters of chemical bonds: 0
15. The number of covalent bond units: 1
Properties and stability
None yet
Storage method
This product should be kept sealed, dry and protected from light.
Synthesis method
1. Prepared by microbial fermentationorproduced by cysteine synthesis.
Purpose
1. Biochemical research.
2.Used in basic cosmetics to protect the skin and prevent skin inflammation.