Isatoic anhydride
Structural formula
| Business number | 039U |
|---|---|
| Molecular formula | C8H5NO3 |
| Molecular weight | 163.13 |
| label |
3,1-Benzoxazine-2,4(1H)-dione, Anthranilic acid N-carboxylic acid anhydride, Fragrance |
Numbering system
CAS number:118-48-9
MDL number:MFCD00006700
EINECS number:204-255-0
RTECS number:DM3100000
BRN number:136786
PubChem number:24895927
Physical property data
1. Characteristics: White prismatic crystals.
2. Density (g/mL,25℃） : Undetermined
3. Relative vapor density (g/mL,Air=1): Undetermined
4. Melting point (ºC): 243 (decomposed).
5. Boiling point (ºC,Normal pressure): Undetermined
6. Boiling point (ºC, KPa): Undetermined
7. Refractive index: Undetermined
8. Flashpoint (ºC): Undetermined
9. Specific optical rotation (º): Undetermined
10. Autoignition point or ignition temperature (ºC): Undetermined
11. Vapor pressure (mmHg, ºC): Undetermined
12. Saturated vapor pressure (kPa, ºC): Undetermined
13. Heat of combustion (KJ/mol): Undetermined
14. Critical temperature (ºC): Undetermined
15. Critical pressure (KPa): Undetermined
16. Oil and water (octanol/Log value of the partition coefficient for water: undetermined
17. Explosion limit (%,V/V): Undetermined
12
8. Surface charge ：0
9. Complexity ：226
10. Number of isotope atoms:0
11. Determine the number of atomic stereocenters:0
12. Uncertain number of atomic stereocenters:0
13. Determine the number of stereocenters of chemical bonds:0
14. Uncertain number of chemical bond stereocenters:0
15. Number of covalent bond units: 1
Properties and stability
Stable at room temperature and pressure, avoid contact with strong oxidants and moisture.
Storage method
Stored in a cool, ventilated warehouse. Keep away from fire and water sources. should be kept away from oxidizer, do not store together. Equipped with the appropriate variety and quantity of fire equipment. Suitable materials should be available in the storage area to contain spills.
Synthesis method
Originated from the reaction of anthranilic acid and phosgene. Dissolve anthranilic acid in hot water and concentrated hydrochloric acid, add phosgene while stirring, and isatoic anhydride will precipitate immediately. The reaction releases heat, adjust the phosgene introduction speed so that the temperature does not exceed 50℃. Continuously pass phosgene 2-4h until the absorption speed slows down significantly. Dry the product in the air at 100℃Dry to get the finished product.
Purpose
Used as a raw material for medicines, pesticides, and dyes, and an important intermediate for the herbicide bendasone.
�Number of stereocenters:0
15. Number of covalent bond units: 1
Properties and stability
Stable at room temperature and pressure, avoid contact with strong oxidants and moisture.
Storage method
Stored in a cool, ventilated warehouse. Keep away from fire and water sources. should be kept away from oxidizer, do not store together. Equipped with the appropriate variety and quantity of fire equipment. Suitable materials should be available in the storage area to contain spills.
Synthesis method
Originated from the reaction of anthranilic acid and phosgene. Dissolve anthranilic acid in hot water and concentrated hydrochloric acid, add phosgene while stirring, and isatoic anhydride will precipitate immediately. The reaction releases heat, adjust the phosgene introduction speed so that the temperature does not exceed 50℃. Continuously pass phosgene 2-4h until the absorption speed slows down significantly. Dry the product in the air at 100℃Dry to get the finished product.
Purpose
Used as a raw material for medicines, pesticides, and dyes, and an important intermediate for the herbicide bendasone.