Oxandrolone

Published by BDMAEE on 2024-05-11 | Permalink

Oxandrolone structural formula

Structural formula

Business number	015Y
Molecular formula	C19H30O3
Molecular weight	306.44
label	(4aS,4bS,6aS,7R,9aS,9bR,11aS)-7-hydroxy-4a,6a,7-trimethyl-tetradecahydroindeno[4,5-h]isochromene-2(1H) -ketone, (4aS,4bS,6aS,7R,9aS,9bR,11aS)-7-hydroxy-4a,6a,7-trimethyl-tetradecahydroindeno[4,5-h]isochromen-2(1H)-one

Numbering system

CAS number:53-39-4

MDL number:MFCD00198944

EINECS number:200-172-9

RTECS number:RN6800700

BRN number:None

PubChem ID:None

Physical property data

1. Character: White odorless crystalline powder

2. Density (g/mL,25/4℃): Undetermined

3. Relative vapor density (g/mL,AIR=1): Undetermined

4. Melting point (ºC):235-238

5. Boiling point (ºC,Normal pressure): Undetermined

6. Boiling point (ºC,5.2kPa): Undetermined

7. Refractive index: Undetermined

8. Flashpoint (ºC): Undetermined

9. Specific optical rotation (º): Undetermined

10. Autoignition point or ignition temperature (ºC): Undetermined

11. Vapor pressure (kPa,25ºC): Undetermined

12. Saturation vapor pressure (kPa,60ºC): Undetermined

13. Heat of combustion (KJ/mol): Undetermined

14. Critical temperature (ºC): Undetermined

15. Critical pressure (KPa): Undetermined

16. Oil and water (octanol/Log value of partition coefficient (water): undetermined

17. Explosion limit (%,V/V): Undetermined

18. Lower explosion limit (%,V/V): Undetermined

19. Solubility:Easily soluble in chloroform, slightly soluble in ethanol, acetone, slightly soluble in ether, and very slightly soluble in water.

Toxicological data

1, acute toxicity: Rat oral LD50: >10 mg/kg; rat intraperitoneal LD50 SPAN>: 4893 mg/kg; Rat subcutaneous LD50: >10 mg/kg ; Mouse oral LD50: 1832 mg/kg;
Mouse abdominal cavityLD50: 922 mg/kg; Mouse subcutaneous: >11 mg/kg; Rabbit Oral LD50: >5 mg/kg
2, reproductive toxicity: Oral administration to female rats TDLo: 1800mg/kg, 2-19 Pregnancy occurs after 3 days; subcutaneous TDLo in female rats: 70mg/kg, 14 Mate in advance;
Female RatTDLo：300mg/kg, 30 days before mating

Ecological data

None yet

Molecular structure data

1. Molar refractive index: 85.10

2. Molar volume (m³/mol）：277.0

3. isotonic ratio(90.2K)：696.3

4. Surface Tension(dyne/cm)：39.8

5. Polarizability(10-24cm³)：33.73

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): 3.7

2. Number of hydrogen bond donors: 1

3. Number of hydrogen bond acceptors: 3

4. Number of rotatable chemical bonds: 0

5. Number of tautomers: 2

6. Topological molecule polar surface area 46.5

7. Number of heavy atoms: 22

8. Surface charge: 0

9. Complexity: 503

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 7

12. Uncertain number of atomic stereocenters: 0

13. Determine the chemical bond stereocenter.�Number: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

None yet

Storage method

Seal and store in a cool place away from light.

Synthesis method

With5-Androster-1-ene–3-17-二Keto or17β-Hydroxy-17-α-Methyl derivatives are used as raw materials.

Purpose

is a male hormone whose main function is protein assimilation. Used to treat high cholesterol and triglycerides.